Figure 4.
Papilloma outgrowth on sites challenged with different doses of CRPV DNA with (B) or without (A) pre-scarification. Two sites on each of five rabbits were challenged with from 0.04µg to 10µg of CRPV either 3 days after scarification (B) or without prior scarification (A). Some sites challenged with low amounts of CRPV DNA (0.04µg) grew papillomas following pre-scarification while scattered papillomas were found on sites challenged without pre-scarification (A).