Table 6.

Evidence-based clinical/therapeutic practices that could be supported in EQUIP-2:

1. Clozapine for patients with severe psychosis, with the goal of increasing the proportion who receive clozapine (Evidence level1 = 1b, [39]);

2. Wellness intervention for elevated weight, with the goals of increasing the proportion of patients receiving antipsychotic medication with less weight gain potential (Evidence level = 1a, [40]), and increasing the proportion of patients who receive a group-based wellness intervention [41]);

3. Family involvement to improve symptom control and functioning (Evidence level = 1a, [42]), with the goals of increasing the proportion of family members who are involved in developing the patient's treatment plan; and

4. Supported Employment for unemployment (Evidence level = 1b, [43]), with the goal of increasing the proportion of patients (who want to work) receiving evidence-based rehabilitation services that lead to competitive employment.

Evidence Pyramid

1a: Evidence obtained from meta-analysis of randomized controlled trials (RCTs)

1b: Evidence obtained from at least 1 RCT

2a: Evidence obtained from at least 1 well-designed controlled study without randomization

2b: Evidence obtained from at least 1 other type of well-designed quasi-experimental study

3: Evidence obtained from well-designed non-experimental descriptive studies, such as comparative studies, correlation studies and case control studies

4: Evidence obtained from expert committee reports or opinions and/or clinical experience of respected authorities