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MiR15a/16-1 cluster inhibits the growth of MEG-01 tumor engraftments in nude mice. (A) Growth curve of engrafted tumors in nude mice injected with MEG-01 cells pretransfected with pRS-E or pRS15/16 or mock transfected. (B) Comparison of tumor engraftment sizes of mock-, pRS-E-, and pRS15/16-transfected MEG-01 cells 28 days after injection in nude mice. (C) Tumor weights ± SD in nude mice.
