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Chemical cross-linking results in formation of oligomers containing ADAR1 and hUpf1. HeLa cell NE was cross-linked by DMS for increasing lengths of time (5–60 min). Aliquots were Western blotted with either anti-ADAR1 antibodies (A) or anti-hUpf1 antibodies (B). Non-cross-linked samples (−) are shown for comparison.
