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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Jan 4;18(3):950–953. doi: 10.1016/j.bmcl.2007.12.044

Table 2.

In vitro anti-leukemic activity of JS-K and its structural analogues.

entry compound IC50, μM
1 JS-K 0.2–0.5
2 6 >50
3 7 3.2
4 8 1.7
5 9 2.5
6 10 2.0
7 11 5.0
8 12a 2.3
9 12b 7.2
10 12c 4.5
11 12d 8.8
12 13a 6.6
13 13b 6.8
14 14a 7.4
15 14b 8.3
16 14c 6.0
17 15a 9.8
18 15b 7.4
19 15c 9.1