Table 1. Groups of transplanted mice and cyclic hormonal activity.
Graft's status | Donor's status | Recipient's status | n | Histology | Fertility | Recovery of cycle | Length of cycle | |
NNF | Fresh (F) | Non mature (N) | Non mature (N) | 27 | 5 | 22 | 16.6±2.5 | 5.1±0.9 |
NAF | Non mature (N) | Adult (A) | 16 | 4 | 12 | 17.5±3.3 | 4.5±1.0 | |
AAF | Adult (A) | Adult (A) | 15 | 7 | 8 | 15.6±2.0 | 5.2±1.1 | |
NNC | Cryopreserved (C) | Non mature (N) | Non mature (N) | 11 | 3 | 8 | 10.2±0.4 | 5.4±0.8 |
NAC | Non mature (N) | Adult (A) | 9 | 6 | 3 | 11.5±0.5 | 6.5±0.7 | |
AAC | Adult (A) | Adult (A) | 8 | 4 | 4 | 12.6±1.5 | 4.6±0.8 | |
Total | 86 | 29 | 57 |
Non-pubertal mouse, 18 day-old was defined as immature and grafted in non-mature (N) or adult mice (A), using cryopreserved (C) or fresh (F) graft. Grafted mice were divided in two groups: mice sacrificed one month after grafting for histological study and the others mated with stud male, to study fertility. n, number of animals/group used for analysis.
Recovery of cycle corresponded to the delay between transplantation and the vaginal opening in non mature recipients and to the delay between transplantation and the recovery of cyclic activity in adult recipients. Length of cycle was defined as the delay in days between two estrus. Data are expressed in days, as mean±SEM.