Table 2. Litter sizes following the first, second and third pregnancies, in each group and secondary infertility.
1st pregnancy | 2nd pregnancy | 3rd pregnancy | Secondary Infertility | |||||
Vaginal plug | Litter size | %/all | Litter size | %/all | Litter size | %/all | ||
NNF | 22/22 | 1.7±0.2 | 36% | 1.6±0.3 | 13.3% | 1.0 | 4.5% | 5.5±2.1 |
NNC | 12/12 | 1.0±0 | 33% | 1.6±0.3 | 25% | 2.0±1 | 16.6% | 5.7±1.3 |
NAF | 8/8 | 4.0±3.0 | 25% | 1.0 | 12.5% | - | - | 3.0±1.7 |
NAC | 8/8 | 1.5±0.5 | 50% | 5.0±0.5 | 37.5% | 1.0 | 12.5% | 8.7±2.6 |
AAC | 4/4 | 1.5±0.5 | 50% | 2.0 | 25% | 2.0 | 25% | 5.5±2.0 |
AAF | 3/3 | 5.0 | 33% | 1.0 | 33% | 1.0 | 33% | 8.0 |
WT | 15/15 | 9.1±0.6 | 100% | 9.4±0.8 | 100% | 9.0±1 | 100% | >18 |
Vaginal plug, number of mice after mating/number of studied mice, by group. %/all, pregnancy rate of females mated. Litter size: mean of pups by female. Secondary infertility was defined as the date, in months after grafting of the ultimate gestation. All data are expressed as mean±SEM.