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. 2008 Apr 16;3(4):e1972. doi: 10.1371/journal.pone.0001972

Table 2. Litter sizes following the first, second and third pregnancies, in each group and secondary infertility.

1st pregnancy 2nd pregnancy 3rd pregnancy Secondary Infertility
Vaginal plug Litter size %/all Litter size %/all Litter size %/all
NNF 22/22 1.7±0.2 36% 1.6±0.3 13.3% 1.0 4.5% 5.5±2.1
NNC 12/12 1.0±0 33% 1.6±0.3 25% 2.0±1 16.6% 5.7±1.3
NAF 8/8 4.0±3.0 25% 1.0 12.5% - - 3.0±1.7
NAC 8/8 1.5±0.5 50% 5.0±0.5 37.5% 1.0 12.5% 8.7±2.6
AAC 4/4 1.5±0.5 50% 2.0 25% 2.0 25% 5.5±2.0
AAF 3/3 5.0 33% 1.0 33% 1.0 33% 8.0
WT 15/15 9.1±0.6 100% 9.4±0.8 100% 9.0±1 100% >18

Vaginal plug, number of mice after mating/number of studied mice, by group. %/all, pregnancy rate of females mated. Litter size: mean of pups by female. Secondary infertility was defined as the date, in months after grafting of the ultimate gestation. All data are expressed as mean±SEM.