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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Drug Alcohol Depend. 2007 Dec 3;94(1-3):56–62. doi: 10.1016/j.drugalcdep.2007.10.005

Figure 1.

Figure 1

The percentage of animals that met criteria for acquisition of cocaine self-administration each day. OVX rats treated with estradiol or vehicle were tested 5 days a week for 5 weeks with increasing doses of cocaine each week.

Open circles - OVX; closed triangles - 1 µg E; closed circles - 2 µg E; open diamonds - 5 µg E; closed squares - E-pellet.

*There was a significant effect of 2 µg treatment on the percentage of rats that acquired self-administration during week 2 relative to the OVX and OVX+pellet groups (p<0.01).