Figure 6. Noradrenaline activates non-selective cation channels in outside-out patches.

A, in an outside-out patch that did not contain any spontaneous activity (i), application of 1 μM noradrenaline activated single cation channels (ii). B, current-voltage relationship plotted from the single cation channel amplitudes recorded from the same patch as A, which had a slope conductance of 25 pS and a reversal potential of +11 mV. The open time (C) and burst duration (D) distributions calculated from the cation channels recorded in A were similar to those calculated for the spontaneous cation channels.