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The amplitude of ICa,L in the presence of Iso (1, 3 or 10 nM), without (□) or with DEANO (100 μM, ▪), was normalized to the basal ICa,L amplitude (set to 100 %). Bars are the means and lines are the s.e.m. of the number of experiments indicated near the bars. Significant differences from basal (*) or Iso levels (†) are indicated as: *P < 0.001; **, ‡P < 0.0001.
