Figure 5. The presynaptic inhibition induced by 5-HT necessitates protein kinase A activation.
In DMV neurones in which 5-HT reduced the amplitude of GABAergic currents, preincubation with the protein kinase A inhibitor Rp-cAMP, but not the protein kinase C inhibitor GF109203X, prevented the 5-HT-mediated presynaptic inhibition. *P < 0.05vs. control.