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. 2001 Mar 15;531(Pt 3):743–756. doi: 10.1111/j.1469-7793.2001.0743h.x

Figure 1. Changes in pHs, pHi and Em in a single EDL fibre evoked by 20 mm lactate in the superfusing solution.

Figure 1

The uptake of lactic acid led to an alkalinization on the surface of the muscle fibre and to an intracellular acidification. The release of lactic acid caused a pHs transient in the acidic direction and caused pHi to return to its control value. The transport of lactate had no effect on Em.