Table 2.

Values of the maximal transport rate, V_max, and of the Michaelis constant, K_m, of lactic acid transport from fibre bundles of soleus and EDL in the absence and presence of 0.01 mm benzolamide

		Lactate-influx		Lactate-efflux
		Control	BZ	Control	BZ
EDL	Vmax (mm min−1)	6.0 ± 0.6	3.3 ± 0.4**	7.8 ± 1.3	4.0 ± 0.7*
	Km (mm)	23 ± 6	20 ± 7	43 ± 16	21 ± 11
Soleus	Vmax (mm min−1)	20 ± 7	15 ± 3	17 ± 2	14 ± 2
	Km (mm)	56 ± 35	54 ± 23	42 ± 9	42 ± 11

Values of V_max and K_m are means ±s.e.m. and were derived from data sets as shown in Fig. 9. The number of fibre bundles studied at each of the lactate concentrations 10, 20, 40, 60 and 80 mm was 4 in the case of EDL and 3 in the case of soleus. Levels of significance of differences in parameters under control conditions and in the presence of BZ are indicated by asterisks and were derived from a statistical analysis of Lineweaver-Burke plots (Sachs, 1999, pp. 553−556):

^*P < 0.05

^**P < 0.002.