Figure 1. The relationship between D_O2 and V_O2 within the hindlimb of one animal in the control group during graded systemic hypoxia.

The filled circles represent the delivery-dependent phase of this relationship and the filled squares show the delivery-independent phase. The two distinct phases were separated using the dual-line least-squares method described by Samsel & Schumacker (1988). The intercept of these two lines defines D_O2,crit. The data shown are representative of the eight different experiments within this group.