Table 1.

Effects of glibenclamide and chelerythrine on action potential duration (ms) during 10 min of no-flow ischaemia and 60 min of reperfusion

		Ischaemia (min)		Reperfusion (min)
	Pre-ischaemia	5	10	5	10	30	60
Control (n = 6)	156 ± 5	119 ± 3*	90 ± 5*	139 ± 4	143 ± 4	151 ± 6	156 ± 5
Glibenclamide (n = 5)	158 ± 5	133 ± 7*	114 ± 5*†	156 ± 6†	156 ± 5	158 ± 5	158 ± 5
Chelerythrine (n = 5)	160 ± 3	142 ± 3*	110 ± 3*†	160 ± 4†	160 ± 4†	160 ± 4	161 ± 7

Glibenclamide (10 μm) or chelerythrine (1 μm) was added from 20 min before ischaemia to 60 min of reperfusion. Data are means ± s.e.m.

^*P < 0.01, significant difference from the pre-ischaemic value

^†P < 0.05, significant difference from the value of control group at the same observation time.