Figure 3. Lack of NMDA receptor activity in EPSCs of an SCN neuron recorded during the subjective day.

For explanation of traces and symbols, see Fig. 2. A, control traces overlap responses evoked during bath application of 50 μmd-AP5. B, I-V relationship for EPSC amplitudes measured at peak latency (13 ms; ▪) and at a latency of 40 ms (•) under control conditions. C, as for B, but now under d-AP5 conditions. Note the absence of a prolonged, d-AP5-sensitive EPSC component.