Table 2.
Aβ and Aβ afferent fibre-mediated EPSCs in sham-operated and SNT rats
| Aδ-mediated EPSCs | Aδ-mediated EPSCs | |||
|---|---|---|---|---|
| Monosynaptic (n) | Polysynaptic (n) | Monosynaptic (n) | Polysynaptic (n) | |
| Control (n = 131) | 51 (39%) | 60 (46%) | 2 (2%) | 18 (14%) |
| Stimulus intensity (μA) | 43 ± 6 | 49 ± 13 | — | 31 ± 1 |
| Range (μA) | 34–61 | 39–93 | 30 and 32 | 30–32 |
| Latency (ms) | < 2.3 | > 2.5 | 1.2 and 1.7 | > 2.5 |
| SNT (n = 37) | 0 | 3 (8%) | 4 (11%) | 30 (81%) |
| Stimulus intensity (μA) | — | 40 ± 7 | 18 ± 4 | 30 ± 2 |
| Range (δA) | — | 36–48 | 15–23 | 24–32 |
| Latency (ms) | — | > 2.5 | < 1.8 | > 2.5 |
As can be seen, most SG neurones in sham-operated (Control) rats displayed either mono- or polysynaptic EPSCs that were mediated by Aδ afferents. A small population of neurones exhibited polysynaptic EPSCs that were mediated by Aβ fibres. This is in contrast to the EPSCs seen in SNT rats, the vast majority of which were mediated by Aβ fibres. Monosynaptic EPSCs mediated by Aβ afferents were slightly increased in number (∼ 11%, 4 of 37 neurones) in SNT rats.