Table 1.
Baseline [AA] (μM) | Infusion rate (mmol kg−1 h−1) | [AA] during infusion (μM) | Fold increase | |
---|---|---|---|---|
Non-essential AAs | ||||
Asp | 34 ± 3 | 0.085 | 83 ± 14 | 2.6 ± 0.4 |
Glu | 135 ± 16 | 0.081 | 258 ± 45 | 2 ± 0.4 |
Gly | 346 ± 40 | 0.108 | 647 ± 62 | 1.9 ± 0.2 |
Ala | 464 ± 37 | 0.181 | 839 ± 83 | 1.8 ± 0.1 |
Ser | 218 ± 14 | 0.082 | 368 ± 43 | 1.7 ± 0.1 |
Gln | 784 ± 48 | — | 889 ± 66 | 1.1 ± 0.1 |
Asn | 81 ± 3 | — | 57 ± 4 | 0.7 ± 0.1 |
Tyr | 107 ± 14 | 0.024 | 78 ± 12 | 0.7 ± 0.1 |
Essential AAs | ||||
Arg | 115 ± 9 | 0.095 | 352 ± 41 | 3.1 ± 0.2 |
Trp | 21 ± 2 | 0.016 | 56 ± 8 | 2.9 ± 0.8 |
Ile | 73 ± 4 | 0.082 | 196 ± 15 | 2.7 ± 0.2 |
Lys | 236 ± 30 | 0.116 | 591 ± 71 | 2.6 ± 0.1 |
Leu | 177 ± 12 | 0.123 | 418 ± 26 | 2.4 ± 0.1 |
Thr | 176 ± 6 | 0.054 | 299 ± 13 | 1.7 ± 0.1 |
Met | 28 ± 2 | 0.019 | 47 ± 1 | 1.7 ± 0.1 |
Val | 234 ± 20 | 0.069 | 348 ± 22 | 1.5 ± 0.1 |
His | 125 ± 8 | 0.031 | 181 ± 14 | 1.4 ± 0.1 |
Phe | 72 ± 3 | 0.029 | 96 ± 4 | 1.3 ± 0.1 |
Concentrations of each amino acid increased significantly P < 0.01 during the amino acid infusion (except for Asn and Tyr, which decreased). Values are means ± S.E.M.