Figure 5. Effect of inhibition of Ca²⁺ influx on chronically increased vascular permeability.

Twenty-four hours after exposure to 1 nm VEGF, L_p was measured on the same vessel during perfusion with 1 % BSA in normal Ringer solution, and then the Ringer solution in the perfusate and superfusate was switched to one containing either 5 mm Ni²⁺(A; n = 6) or 100 μm SK&F 96365 (B; n = 3). L_p measurements are expressed as the mean (±s.e.m.) fraction of the permeability on day 2 before Ni²⁺ or SK&F 96365 perfusion.