Figure 6. Effect of VEGF and ATP perfusion on chronically increased permeability and endothelial [Ca²⁺]_i.

VEGF (n = 5) and ATP (n = 4) both increase L_p 24 h after perfusion compared to 1 % BSA (▪, left-hand axis, n = 11). However the endothelial [Ca²⁺]_i (right-hand axis) was no greater 24 h after ATP (n = 4) or VEGF (n = 5) perfusion () than it was in vessels in which calcium was measured without agonist perfusion (□, n = 16). *P < 0.05 compared to 1 % BSA.