Table 1.
The amplitude and time course of evoked and spontaneous NTIs recorded from polymodal and cold-sensitive receptors
n | Conduction velocity (m s−1) | +Peak(μV) | −Peak(μV) | +dV/dt max(normalized) | −dV/dt max(normalized) | Ratio | |
---|---|---|---|---|---|---|---|
Polymodal | |||||||
Evoked | 36 | 1.1 ± 0.1 | 40 ± 3 | −9 ± 1 | 2900 ± 127 | −4119 ± 172 | 0.74 ± 0.05 |
Spontaneous | 36 | — | 34 ± 2 | −7 ± 1 | 2683 ± 120 | −4186 ± 212 | 0.70 ± 0.06 |
Difference | — | — | 5 ± 1** | −1 ± 1 | 211 ± 108* | 65 ± 122 | 0.04 ± 0.02 |
Cold | |||||||
Evoked | 51 | 1.7 ± 0.1†† | 50 ± 4† | −8 ± 1 | 3260 ± 103†† | −3449 ± 173†† | 0.99 ± 0.05 |
Spontaneous | 51 | — | 47 ± 4†† | −9 ± 1 | 3386 ± 107†† | −3450 ± 179†† | 1.07 ± 0.05 |
Difference | — | — | 3 ± 1** | 1 ± 1 | −146 ± 89* | −126 ± 59 | −0.08 ± 0.03** |
The maximum rates (V s−1) of rise and fall were normalized with respect to NTI amplitude by dividing them by the peak-positive amplitude (see Methods). The ratio was calculated by dividing +dV/dt max by –dV/dt max. The difference was calculated by subtracting the values for the spontaneous NTIs from those for the evoked NTIs. The significance of the difference was calculated using one-sided, paired t tests (P < 0.05)
The maximum rates (V s−1) of rise and fall were normalized with respect to NTI amplitude by dividing them by the peak-positive amplitude (see Methods). The ratio was calculated by dividing +dV/dt max by −dV/dt max. The difference was calculated by subtracting the values for the spontaneous NTIs from those for the evoked NTIs. The significance of the difference was calculated using one-sided, paired t tests (P < 0.01).
Statistical comparisons between the evoked or spontaneous NTIs from the polymodal and cold-sensitive receptors were made using unpaired t tests (P < 0.05)
Statistical comparisons between the evoked or spontaneous NTIs from the polymodal and cold-sensitive receptors were made using unpaired t tests (P < 0.01).