Table 2.

Effects of bath applied 1 μM TTX on the amplitude and time course of the NTIs recorded from polymodal and cold-sensitive receptors

	n	+Peak	−Peak	+dV/dt max (normalized)	−dV/dt max (normalized)	Ratio
Polymodal	11	0.67 ± 0.04**	0.72 ± 0.12*	1.20 ± 0.13	0.73 ± 0.09**	2.13 ± 0.50*
Cold	14	0.84 ± 0.06**	1.01 ± 0.18	1.35 ± 0.27	0.79 ± 0.11*	1.72 ± 0.17**

All values are the mean ±s.e.m. of the test (1 μM TTX) values expressed relative to the control values. Prior to calculating the relative change in the maximum rates (V s⁻¹) of rise and fall, the values were normalized with respect to NTI amplitude by dividing them by the peak-positive amplitude (see Methods). The ratio was calculated by dividing +dV/dt max by −dV/dt max. Statistical comparisons were made between control and test values using one-sided, paired t tests

^*(P < 0.05)

^**(P < 0.01).