Figure 6. Mutations in the Kir1.1 P-helix abolish K+-dependent gating.
A and B, complete recovery of currents in Kir1.1(L136I) and Kir1.1(V140T) channels. Experimental conditions as in Fig. 2B. C, relative recovery of currents from experiments as in A and B (acidification periods of 50 s); bars represent means ±s.d. of 5 (Kir(L136I)) and 12 (Kir1.1(V140T)) experiments. Data for Kir1.1 and Kir1.1(K80M) were added for better comparison.