Skip to main content
. 2001 Aug 1;534(Pt 3):641–650. doi: 10.1111/j.1469-7793.2001.t01-1-00641.x

Figure 2. Effects of L-type VGCC blockade and ROC/SOC blockade on PE-mediated tonic contraction.

Figure 2

A, a representative tension trace showing that 10 μm nifedipine completely abolished an 80 mm [K+]o-mediated tonic contraction in rings of rabbit IVC pretreated with 10 μm phentolamine. B, L-type VGCC blockade with 10 μm nifedipine partially inhibited a PE-mediated tonic contraction (P < 0.05, Wilcoxon signed-rank test), while additional ROC/SOC blockade with 50 μm SKF96365 completely abolished the remaining tonic contraction.