Figure 2. Rate dependency of 293B-sensitive current (IKs).

A and B, examples of action potential and I_293B recorded at a cycle length (CL) of 1000 (A) and 250 ms (B) according to protocol A; the two CLs were tested within the same cell. C-E, comparison between cycle lengths of 1000 and 250 ms for mean repolarization current density (C), time course of I293B conductance (g_293B) during the action potential (dynamic conductance, D) and the ratio between I_293B and total repolarizing current (I_tot, E). In D, mean traces (thick lines) and their confidence limits (thin lines) are shown; the arrows mark instantaneous conductance. C-E, mean data from 13 cells; *P < 0.05.