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. 2001 Sep 15;535(Pt 3):729–740. doi: 10.1111/j.1469-7793.2001.00729.x

Table 4.

Gating properties of wild-type and hybrid αY93F and αW149F receptors in the presence of TMA

Receptor β (s−1) EC50 (μm) n α (s−1) Θ
wild-type 8156 ± 382 2375 ± 265 1.2 ± 0.1 1508 ± 205 5.4
αY93F hybrid 228 ± 67 2474 ± 1037 1.7 ± 1.2 3068 ± 68 0.074
αW149F hybrid 844 ± 430 7041 ± 4862 1.7 ± 0.6 2001 ± 57 0.42

The values for the wild-type receptor are from Akk & Auerbach (1996). β was determined from the saturation of the effective opening rate by fitting to eqn (1). α was determined in the presence of 2 mM TMA (pipette potential = 50–60 mV). Θ is β/α.