A, myogenin; B, MRF4; C, MyoD; D, Myf5. Pre, before leg immobilixation; Post, 2 weeks after leg immobilization. R3, 3 weeks of rehabilitation training; R10, 10 weeks of rehabilitation training. Values are means ±s.e.m. of eight observations and are expressed relative to the baseline values (Pre). *Significant treatment effect compared with placebo.