Table 1.

Potency of allosteric modulators of GABA_A receptor in control and epileptic DGCs

Drug	Epileptic DGCs	Control DGCs
GABA	32.6 ± 6.1 μM	29.2 ± 4.3 μM
Allopregnanolone	92.7 ± 13.4 nM*	12.9 ± 2.3 nM
PS	17.4 ± 2 μM	13.1 ± 1.6 μM
Diazepam	69 ± 14 nM*	29.9 ± 5.7 nM
Zolpidem	93.7 ± 6.5 nM*	44.2 ± 8.6 nM
Zn2+	19 ± 6 μM*	94.7 ± 7.9 μM

Values are means ±s.e.m.

^*P < 0.05.