Table 1.
Condition | Trial 1: phentolamine | Trial 2: phentolamine and propranolol | Trial 3: phentolamine propranolol and l-NMMA | |
---|---|---|---|---|
PO2 (mmHg) | Normoxia | 88.9 ± 1.9 | 86.4 ± 2.2 | 89.1 ± 3.7 |
Hypoxia | 42.2 ± 1.4 * | 43.8 ± 2.0 * | 44.1 ± 1.8 * | |
PCO2 (mmHg) | Normoxia | 40.8 ± 1.2 | 35.8 ± 5.0 | 39.8 ± 1.4 |
Hypoxia | 37.6 ± 1.3 | 37.7 ± 1.2 | 37.5 ± 1.8 | |
End-tidal CO2 (%) | Normoxia | 6.2 ± 0.4 | 6.2 ± 0.4 | 6.1 ± 0.4 |
Hypoxia | 5.8 ± 0.4 * | 5.8 ± 0.4 * | 5.8 ± 0.4 * | |
pH | Normoxia | 7.39 ± 0.01 | 7.38 ± 0.01 | 7.38 ± 0.01 |
Hypoxia | 7.41 ± 0.01 * | 7.42 ± 0.01 * | 7.41 ± 0.01 * | |
Hb saturation (%) | Normoxia | 96.6 ± 0.3 | 96.1 ± 0.2 | 96.5 ± 0.6 |
Hypoxia | 77.9 ± 1.7 * | 79.8 ± 2.0 * | 80.3 ± 2.0 * |
Hb, haemoglobin.
P <0.005, Hypoxia vs. Normoxia.