Figure 7.
(a) p65 levels determined by Western blotting and (b) p65 activity in the nuclear fraction of extensor digitorum longus muscles from septic rats incubated for 2 hours in the absence or presence of 100 μM curcumin. Results are means ± SEM with n = 4 in each group. AU: arbitrary units. *P < .05 versus control by Student’s t-test. (c) The effect of the p65 inhibitor PTD-p65-P1 on protein breakdown rates in incubated muscles from septic rats. Muscles were incubated in the presence of 100 μM PTD-p65-P1 or 100 μM of the inactive peptide PTD as control. Results are means ± SEM with n = 7 in each group. *P < .05 versus PTD by Student’s t-test.