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. 2008 Apr;131(4):307–323. doi: 10.1085/jgp.200709915

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Copyright © 2008, The Rockefeller University Press

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Figure 4. — Effects of BHQ and GPN on undifferentiated PC12 cells. Ca²⁺ transport curves (−d[Ca²⁺]_cyt/dt vs. [Ca²⁺]_cyt) are shown. (A) The light gray data points show cells treated with 10 μM BHQ in addition to the 4-blocked protocol (n = 15). The dark gray data points show residual transport in the 4-blocked cells of Fig. 1 with a superimposed smooth curve calculated from the residual transport function in a kinetic model discussed in Appendix. (B) The gray curve shows cells treated with GPN, whereas the black curve shows a truncated version of the control Ca²⁺ transport curve from Fig. 1.