Pedigree and haplotypes for family VAF-1. Black symbols indicate individuals affected with atrial fibrillation (AF); gray, obligate carriers; and diagonal lines, deceased individuals. Proband is indicated by arrow. Underlined numbers indicate unaffected individuals used in linkage analyses. Results of genotypic analysis are shown for markers D5S2088, D5S406, D52054, D5635, D5807, and D5S1486 below each individual. Vertical black line to the left of some series of numbers indicates disease haplotype. One consanguineous marriage is indicated by =.