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. Author manuscript; available in PMC: 2009 Feb 26.
Published in final edited form as: Eur J Pharmacol. 2007 Nov 28;581(1-2):19–29. doi: 10.1016/j.ejphar.2007.11.053

Fig. 10. The effect of saturating concentrations of GTPγS on the PWR spectra of cannabinoid agonist/ human cannabinoid CB1-myc-His6 receptor /Gi1 ternary complexes.

Fig. 10

PWR spectra of (A) WIN 55,212-2- or (B) CP 55,940-bound human cannabinoid CB1 receptor-containing proteolipid bilayers in the absence (1) or presence (2) of saturating concentrations of Gi1 protein (80 nM). (3) PWR spectra after addition of saturating concentration (200 nM) of GTPγS to the agonist/receptor/Gi1 ternary complexes. The figure shows only PWR spectra obtained with s-polarized light; similar results were obtained with p-polarization (not shown). The spectra are representative from three independent experiments.