Table 2.
Selected hematology parameters in female rats exposed to MSC
| Female RBC (106/μL) | Female HCT (%) | Female HGB (g/dL) | Female MCV (fl) | Female MCH (pg) | Female reticulocyte (%) | Female platelet (103/μL) | Prothrombin time (sec) | |
|---|---|---|---|---|---|---|---|---|
| Vehicle control | 7.8 ± 0.3 | 47.1 ± 1.7 | 15.8 ± 0.4 | 60.2 ± 1.6 | 20.2 ± 0.6 | 4.2 ± 0.9 | 1198 ± 133 | 15.2 ± 0.5 |
| MSC – 0.15 mg/kg | 7.9 ± 0.4 | 47.4 ± 2.1 | 15.9 ± 0.7 | 60.5 ± 1.7 | 20.3 ± 0.6 | 3.9 ± 0.7 | 1194 ± 102 | 15.7 ± 0.5 |
| MSC – 0.30 mg/kg | 7.8 ± 0.3 | 45.6 ± 1.9 a | 15.3 ± 0.7 a | 58.6 ± 1.8 b | 19.7 ± 0.6 a | 4.3 ± 0.8 | 1067 ± 111 a | 16.1 ± 0.5 |
| MSC – 0.60 mg/kg | 7.4 ± 0.4 b | 43.2 ± 1.8 b | 14.8 ± 0.6 b | 58.3 ± 1.6 b | 20.0 ± 0.5 | 5.3 ± 1.2 b | 880 ± 183 b | 17.4 ± 2.4 b |
All values are Mean ± Standard Deviation.
p < 0.05 versus sex-matched vehicle control group.
p < 0.01 versus sex-matched vehicle control group.