Figure 3.

The cavities of hVAP-1. A dot surface of the hVAP-1 dimer is shown as a side (A,B), bottom (C), and top (D) view; domains are colored as in Figure 1 ▶. The active site cavities A1 and B1 of subunits A and B, respectively, as well as the central cavities C1–C3 and the cavities A2 and B2 of the subunits A and B, respectively, are shown as light gray surfaces. The putative N-linked glycosylation sites N1–N6 are labeled, and the carbohydrate visible in the X-ray structure are drawn as yellow spheres. The locations of the RGD cell attachment sites are indicated.