Figure 4.

(A) Spatial location of the residues which are specific to APETx1 (right) and APETx2 (left). The residues are colored green for polar uncharged residues, blue for basic residues, red for acidic residues, purple for aromatic residues, and yellow for aliphatic residues. (B) Location of residues with similar properties in PcTx1 (ASIC1a) and APETx2 (ASIC3). The residues are colored green for polar uncharged residues, blue for basic residues, red for acidic residues, purple for aromatic residues, and yellow for aliphatic residues. The dipole moments are represented by an arrow.