Table 2.
Major saccharide determinants of N- and O-glycoproteins that inhibited the agglutinating activity of the lectins from Hypnea musciformis (HML) and Hypnea cervicornis (HCA)
| Saccharide determinant | ||
| N-Glycoproteins | ||
| Porcine thyroglobulin; human and bovine lactoferrin | ||
| NeuAcα 2–6 Gal β 1–4 GlcNAc β 1–2 Man | Fuc α 1-6 | |
| |α1–6| Man β 1–4 GlcNAc β 1–4 GlcNAc β 1-ASN /α 1-3 |
||
| NeuAcα 2–6 Gal β 1–4 GlcNAc β 1–2 Man | ||
| O-Glycoproteins | ||
| Ovine submaxillary mucin | NeuAc α 2–6 GalNAc α 1Ser/Thr | (Sialyl Tn) |
| Desialylated ovine submaxillary mucin | GalNAc α 1Ser/Thr | (Tn antigen) |
| Porcine stomach mucin | ||
| GalNAc α 1Ser/Thr | ||
| Galβ 1–3 GalNAc α 1Ser/Thr | (T antigen) | |
| GlcNAc α 1–4-Gal | ||
| Fuc α 1–2 Gal- | (Blood group H) | |
| GalNAc α 1–3[Fucα 1–2] Gal- | (Blood group A) | |
| Bovine submaxillary mucin | ||
| NeuAc α 2–6 GalNAc α 1Ser/Thr | ||
| NeuAc α 2–6[GlcNAc β 1–3] GalNAc α 1Ser/Thr | (sialyl core 3) | |
| GlcNAc β 1–3 GalNAC α 1Ser/Thr | (core 3) | |
| Fuc α 1–2 Gal- | ||
| GalNAc α 1–3 [Fuc α 1-2] Gal- | ||
| Asialofetuin | ||
| Gal β 1–3 GalNAc α 1Ser/Thr | (core 1) | |
The putative epitope recognized by HML and HCA within N-glycoproteins is highlighted in boldface.