Table 1.

Class-specific residues in the sugar-binding loop

Enzyme		Consensus sequence		Partition	No.sequences
PNGM	323	-G - E - S g h	329	3	9
PMM	323	-- G E mS g H	329	3	16
PGM	373	-c G E E s f g	380	2	27
PAGM	380	FE A N G H G T	387	2	7

Capital letters indicate class-specific residues; lowercase are highly conserved. Partition number indicates level in multiple sequence alignment at which the consensus sequence was derived.