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(A) Representation of linking between the three-, four-, and five-disulfide classification wheels. The three-disulfide classification wheel is shown in green, the four-disulfide classification wheel is shown in blue, and the five-disulfide classification wheel is shown in red. (B) The subset of links in panel A that form the subgraph encompassing the trypsin family. (C) Comparison of different disulfide patterns in the subgraph containing trypsin family members.
