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Multiple alignment of the primary sequences corresponding to the ectodomain of β-DG from different species. Positions refer to the human DG sequence. The presence of an identical residue in all of the sequences analyzed is indicated by an asterisk (*); of conserved substitutions, by a colon (:); of semiconserved substitutions, by a period (.). The bold sequence corresponds to the binding epitope for α-DG (Bozzi et al. 2003).
