Table 1.

Comparison of ΔG°, ΔG°/n and ΔG_effof various multimeric proteins

Proteins	Oligomeric state	ΔG° (kcal/mole of n-mer)	ΔG°/n (kcal/mole of monomer)	ΔGeff (kcal/mole of monomer)
Trp aporepressor	2	23.3 ± 0.9a	11.7 ± 0.5	9.1 ± 0.5
HIV-1 protease	2	14.2 ± 1.4b	7.1 ± 0.7	4.6 ± 0.7
Arc repressor	2	11c	5.5	3.0
Adenylate kinase	3	30.5d	10.2	6.8
T4 fibritin	3	21.3 ± 0.1e	7.1 ± 0.03	3.7 ± 0.03
p53	4	29.5	7.4h	3.5
SecB	4	28 ± 2f	7.0 ± 0.5	3.1 ± 0.5
4-Oxalocrotonate tautomerase	6	68 ± 3g	11.3 ± 0.5	7.0 ± 0.5
GroES	7	63	9.0i	4.5

The ΔG° value for each protein was collected from the literature. For p53 and GroES, ΔG° values were calculated from the ΔG°/n reported in the literature. The ΔG_eff value of each protein was calculated with equation 6, with a protein concentration of 100 μM in monomer units.

^aGittelman and Matthews 1990; ^bGrant et al. 1992; ^cBowie and Sauer 1989; ^dBackmann et al. 1998; ^eGüthe et al. 2004; ^fPanse et al. 2000; ^gSilinski et al. 2001; ^hJohnson et al. 1995; ⁱBoudker et al. 1997.