Table 3.
CRF2(a)-C-(His)6 receptor NT | N-(His)6-CRF2(a) receptor NT | |
Ligand | EC50 [nM] | EC50 [nM] |
Rat urocortin 1 (8–40) | 45.6 ± 4.9 | 71.0 ± 10.1 |
Astressin | 6.8 ± 1.5 | 4.6 ± 0.5 |
The data are means of at least three different experiments performed in triplicates using [125I]Tyr0-urocortin as radioligand.