Table 1.

The parameters used during the clustering of the interfaces

Cycle	Number of interfaces	Relative connectivity score	Minimal % amino acid identity	Maximal amino acid size difference between interfaces
A	21,686 → 16,446	0.9	90	0
B	16,446 → 9637	0.9	80	3
C	9637 → 6647	0.8	50	10
D	6647 → 5332	0.7	25	20
E	5332 → 4429	0.6	10	40
F	4429 → 3799	0.5	0	50