Table 3.

Residue propensities of amino acids

Residue type	Type I	Type II	Type III	All
G	0.699	0.599	0.644	0.671
A	0.966	0.761	0.897	0.900
C	1.780	1.338	1.153	1.427
D	0.966	0.602	0.775	0.826
E	0.725	0.988	0.982	0.866
F	1.409	1.373	0.956	1.213
H	1.331	0.779	0.900	1.076
I	1.044	1.469	0.999	1.068
K	0.611	0.578	0.887	0.732
L	1.073	1.532	1.039	1.127
M	1.289	0.839	0.982	1.083
N	0.908	1.215	1.261	1.109
P	0.987	0.343	0.626	0.735
Q	0.910	1.1014	0.951	0.954
R	1.137	0.754	1.276	1.140
S	1.027	1.029	0.864	0.955
T	0.878	0.741	1.080	0.942
V	0.999	1.112	0.865	0.986
W	0.969	0.856	1.260	1.075
Y	1.560	1.379	1.102	1.318
A,P,I,L,M,V	7.50–38%	7.42–40%	6.36–34%
D,E,R,K	3.45–17%	2.92–16%	3.93–21%
N,Q,S,T	3.73–19%	3.98–20%	4.15–22%
W,Y,F,H	5.27–26%	4.40–24%	4.22–23%

The first column is the type of the amino acid. The second, third, and fourth columns are the propensities for Type I, II, and III clusters, respectively. The last column gives the overall propensities summed over all types of interfaces. The last four rows are the sum of the propensities for hydrophobic, polar, charged, and aromatic residues, respectively. The first number gives the cumulative effect of all the residues in the four classes, the second number gives the percentage of the each class.