Figure 2.

Structural alignment of DHODR, DHODH, and DHODC sequences. The structural elements correspond to the DHODR structures. α-Helixes in the central barrel are named α1–α8 and β-sheets in the barrel are named β1–β8. α-Helixes and β-sheets outside the barrel are named αA-αE and βA-βE. The predicted transmembrane helix (TM) is labeled in blue. The predicted targeting signal is labeled in orange. Identical residues are labeled with a grey box. This figure was produced using the program Indonesia (D. Madsen, P. Johansson, S. Arent, M.R. Harris, and G.J. Kleywegt, unpubl.; http://alpha2.bmc.uu.se/dennis/).