Figure 4.

Conformational map of the N-terminal peptide (FP) of HIV-1 gp41 in HFIP, SDS micellar, and PBS environments, as estimated from the FTIR spectra of ¹³C-labeled peptides. Amino acids are represented by three-letter codes. Codes (in parentheses) for peptide conformations are: β-sheet (β),β-turn (βT), α-helix (α) and random (R). For FP (470 μM) in HFIP:water:formic acid (70:30:0.1. v/v), conformations were earlier determined from native and ¹³C-enhanced FTIR spectra (Gordon et al. 2002). For FP in SDS micelles (P/L = 1 : 200) in PBS (pH 7.4), conformations were determined from the FTIR spectra of Figures 3 ▶, S-1, and 5D–F. For FP (470 μM) in PBS (pH 7.4), conformations were determined from the FTIR spectra of Figures 5A ▶–C and 6.