Table 1.

Comparison of d_S and d_N substitutions per 100 sites in het-c

Alleles/species	n	Specificity region		Non-specificity region
		dS	dN	dS	dN
OR-type*	17	25.5 (5.6)	10.3 (1.7)	19.2 (3.5)	2.1 (0.6)
GR-type*	8	16.2 (5.1)	6.0 (1.5)	14.0 (3.3)	1.4 (0.6)
PA-type†	15	16.3 (4.5)	21.5 (2.9)	13.8 (3.0)	1.2 (0.4)
All†	40	38.0 (7.1)	20.4 (2.8)	24.5 (3.5)	2.6 (0.6)
N. crassa‡	15	23.9 (7.8)	17.0 (3.3)	20.5 (4.3)	2.1 (0.7)
Sordaria†	5	37.0 (8.9)	20.3 (3.8)	27.3 (5.5)	1.5 (0.7)

Specificity and non-specificity region refer to the codons of filled and clear bar regions in Fig. 3, respectively. n, the number of alleles surveyed. Standard errors are in parentheses. GR, OR, and PA-types refer to het-c^GR, het-c^OR, and het-c^PA allelic specificity types, respectively. Test of hypothesis: d_N/d_S ratio has no significant difference in the two regions (26, 27). *P < 0.05,  

^†P < 0.001, and  

^‡P < 0.01.