Spectra of mutations reverting the hom3–10 allele in wild-type and different mutant strains. Nucleotides 623–682 of the sequenced region is shown. Each independent frameshift event detected is indicated over the sequence with a Δ. Complex mutations that include base changes are shown below the sequence in parentheses. In the wild–type strain, two identical complex events were observed. The total number of isolates analyzed was: wild type, 24; msh6, 28; mlh3, 24, and mlh3 msh6, 30.