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. 2003 Nov 1;112(9):1342–1350. doi: 10.1172/JCI18607

Figure 3.

Figure 3

Effects of abrogated TGF-β signaling on serum lipoproteins and Ab’s to modified LDL. (a) FPLC analysis of lipoprotein profiles from sera of 12-week-old mice. The cholesterol concentration in each fraction (y axis) is plotted against retention time (x axis); curves show mean ± SD for E0 × CD4dnTβRII (gray line) and E0 (black line) sera (n = 9 per group). The lipoprotein profile of a human serum is plotted for reference. CR, chylomicron remnants. (b) Titers of IgM, IgG1, IgG2a, and IgG2b Ab’s to MDA-LDL (OD values of ELISA) from 12-week-old E0 × CD4dnTβRII and E0 mice; individual values for each mouse and medians for each group are displayed.